Managing forest health is a critical challenge for forest managers and policymakers worldwide, especially in connected forests where ecological and socio-economic linkages are tightly intertwined. Conservation and sustainable management of forest ecosystems require the development and implementation of comprehensive strategies that address the complex interactions between natural and human-driven stressors affecting forest health. In this chapter, we review the main drivers of forest health degradation and provide an overview of the approaches and tools that can be used to monitor and manage forest health. We highlight the importance of integrating practical knowledge with scientific information to enhance the resilience of forest ecosystems to global environmental changes. Finally, we discuss the challenges and opportunities associated with managing forest health in connected forest landscapes, and we suggest possible strategies to improve forest health management.