Bioactive Constituents from Boswellia papyrifera

Washington D.C.

2005

S. 189-193

Bandaufführung

10847S

171140

Phytochemical investigation of the stem bark extract of Boswellia papyrifera afforded two new stilbene glycosides, trans-4¢,5-dihydroxy-3-methoxystilbene-5-O-{R-L-rhamnopyranosyl-(1f2)-[R-L-rhamnopyranosyl-( 1f6)]-â-D-glucopyranoside (1), trans-4¢,5-dihydroxy-3-methoxystilbene-5-O-[R-L-rhamnopyranosyl- (1f6)]-â-D-glucopyranoside (2), and a new triterpene, 3R-acetoxy-27-hydroxylup-20(29)-en-24-oic acid (3), along with five known compounds, 11-keto-â-boswellic acid (4), â-elemonic acid (7), 3R-acetoxy-11-keto- â-boswellic acid (8), â-boswellic acid (9), and â-sitosterol (10). The stilbene glycosides exhibited significant inhibition of phosphodiesterase I and xanthine oxidase. The triterpenes (3-9) exhibited prolyl endopeptidase inhibitory activities.