Struktur der Triterpen-Sapogenine von Aesculus glabra

Structure of Triterpene-Sapogenins of Aesculus glabra

Stuttgart

1984

S. 391-394

1 Abb., 1 Tab., 11 Lit. Ang.

Bandaufführung

10214S

145424

After extraction of coarsely ground seeds of Aesculus glabra Willd. with 80 % methanol the saponin fraction was submitted to enzymatic and acid hydrolysis, giving qualitatively identical TLC-spectra of the sapogenins. For Separation of the obtained sapogenins silica gel-columns with chloroform-methanol-water mixtures as mobile phases were employed. Five main components (genins G-A to G-E), identified as 21,22-diangeloyI-barringtogenol C, 21,22-diangeloyl-R1-barrigenol, 21-angeloyl-barringtogenol C, 22-angeloyl-R1-barrigenol and 21-angeloyl-R1-barrigenol have been isolated. Structure elucidation was accomplished by 1H-NMR and mass spectrometry of the genins, their acetates and several isopropyliden derivatives. The acid free sapogenins barringtogenol C and R1-barrigenol (G-F and G-G) were found and identified by thin layer chromatography.